1INOE 2000
The first water channel protein (WCP) was discovered in the 1980s during studies of the human red blood cell membrane. In the 1990s it became obvious that WCPs constitute a large family of membrane proteins that are present in all kingdoms of life: plants, microorganisms (archaea, bacteria, yeast, and protozoa), and animals including humans. WCPs exist in three subfamilies: (1) aquaporins (AQPs) that are mainly water channels; (2) aquaglyceroporins (and glycerol facilitators) that convey water and/or other small molecules across membranes; and (3) S-aquaporins “superaquaporins” or subcellular AQPs.
Second World Congress on Water Channel Proteins
76-79
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